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Our Research 

We demonstrate how lessons learnt from Biology can be applied to develop nanotechnology using synthetic chemistry. Mimicking biological systems using synthetic molecules is an ideal way to construct artificial nanotechnology that is diverse, robust and functional. Our research focuses on kinetically controlled supramolecular chemistry and polymer nanotechnology.

 

We are developing synthetic approaches to nanoscale communication. Our research is inspired by biology, where communication is essential for coordination in all forms of life. For example, communication allows single cell organisms to form colonies and permits organs to work together to maintain homeostasis in humans. Communication occurs either directly by transfer of signalling molecules, such as hormones and pheromones, or indirectly by changes in the surrounding environment. Our research will mimic these natural forms of communication using synthetic chemistry at the nanoscale.

 

Areas of interest

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Supramolecular chemistry We are looking to apply crown ether active template synthesis (developed by Steve during his PhD) to complex systems. This kinetically controlled rotaxane synthesis permits the capture of molecular rings into a variety of structures using simple organic transformations.

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For more information, see:

ChemSystemsChem 2024, 6, e2023008.
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image credit: Anna Tanczos, Sci-Comm studios

Polymer Nanotechnology We are interested in developing new ways to regulate polymer self-assembly using kinetic control. This will allow us to make assemblies that are responsive and adaptive, as well as making unusually shaped nanoparticles.

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For a review from the group, see:

J. Am. Chem. Soc. 2024, 146, 18781–18796.

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image credit: Anna Tanczos, Sci-Comm studios

Funding

We are very grateful to the following funders for making our research possible:​

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